Folic acid and Lipoic acid

Folic acid tablets are used by pregnant women for the facilitation of growth factor. Folic acid derivatives are tri glutamyl peptides and hepta glutamyl peptides. These folic acid derivatives play an important role in the formation of normal erythrocytes. Folic acid can be used for the curing of nutritional anemia. Folic acid, on reduction yields coenzymes. An enzyme called L-folate reductase reduces folic acid into dihydrofolic acid. Dihydrofolic acid is then reduced to tetrahydrofolic acid by dihydrofolic reductase. Tetrahydrofolic acid is used in Serine-Glycine interconversion and thymidine-5’-phosphate biosynthesis.

Lipoic acid is responsible for growth factor in certain bacteria and protozoa. Lipoic acid is found in liver and yeast. It exists in oxidized as well as in reduced forms due to its ability to undergo reduction. Here a disulfide linkage is responsible for reduction. Lipoic acid is acts as a cofactor of the multienzyme complexes pyurvic dehydrogenase and α-ketoglutaric dehydrogenase.